PLLA Fillers vs. Juvélook: Understanding Collagen Boosters for Natural Volume and Firmness

1. What is a PLLA Filler?

Ingredient: PLLA (Poly-L-Lactic Acid) is a biodegradable polymer derived from plants. When injected into the dermis, it stimulates collagen production.
Effect: Collagen is generated gradually, improving skin volume, elasticity, and providing a lifting effect. Results can last for more than two years.
Aftercare: For five days after the procedure, massage the treated area five times a day for five minutes each session (the “555 rule”) to prevent nodules (hard lumps).
Precautions: Side effects may include bruising, swelling, and, rarely, nodules or granulomas. Volume results may be affected by significant weight changes.

Ingredient: Juvélook is a collagen booster made from a combination of PDLLA (Poly-d,l-lactic acid) and hyaluronic acid (HA).
Mechanism: Injected into the dermis, it stimulates collagen production while the hyaluronic acid provides immediate volume. Over time, it improves skin elasticity, fine wrinkles, and skin texture.
Effect: Collagen production starts to show results after 4–6 weeks, with peak effects at 3–6 months and results lasting 1–2 years.
Features: The particles are small and round, reducing the risk of nodules. It is biodegradable, leaving almost no residue in the body.
Aftercare: Avoid makeup, washing the face, intense exercise, saunas, alcohol, and smoking for 24 hours after the procedure. Cold compresses are recommended.
Precautions: Side effects are generally mild, with minimal pain, bruising, or injection marks. Nodules are rare but can be managed with massage if they occur.

Item	PLLA Filler (Sculptra, etc.)	Juvélook (PDLLA + HA)
Main Ingredient	PLLA (Poly-L-Lactic Acid)	PDLLA (Poly-d,l-lactic acid) + HA
Mechanism	Stimulates collagen, gradual volume	Collagen stimulation + immediate volume, skin texture improvement
Onset of Effect	Gradual, starting after 4–6 weeks	Immediate with HA, gradual with collagen
Peak Effect	6–12 months	3–6 months
Duration	Over 2 years	1–2 years
Nodule Risk	Relatively high	Low
Aftercare	Massage required (555 rule)	Simple care, massage if needed
Side Effects	Bruising, swelling, nodules, granulomas	Bruising, swelling, rarely nodules
Natural Appearance	Gradual, natural collagen volume	Immediate with HA + natural collagen volume
Treatment Areas	Cheeks, nasolabial folds, forehead, chin	Cheeks, wrinkles, pores, scars, hollows

Both PLLA fillers and Juvélook boost collagen production to improve skin volume and firmness. However, Juvélook also offers immediate volume and skin texture improvement thanks to its hyaluronic acid component.
PLLA fillers last longer but require careful management to prevent nodules. Juvélook has fewer side effects and is easier to manage, making it a good choice for those seeking natural changes.
Always consult with a medical professional before and after the procedure and follow the specific care instructions for each product to ensure safe and effective results.

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